Nano Archive

Toxicity of citrate-capped AuNPs: an in vitro and in vivo assessment

Sabella, Stefania and Brunetti, Virgilio and Vecchio, Giuseppe and Galeone, Antonio and Maiorano, Gabriele and Cingolani, Roberto and Pompa, Pier Paolo (2011) Toxicity of citrate-capped AuNPs: an in vitro and in vivo assessment. Journal of Nanoparticle Research, 13 (12). pp. 6821-6835.

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In this study, we show that 15 nm citrate-capped AuNPs exert a remarkable toxicity in living systems. The assessment was performed by using well-characterized AuNPs, the combination of in vitro and in vivo models (namely two different cell lines and Drosophila melanogaster), exposure to low dosages of nanoparticles (in the sub-nanomolar concentration range), along with the application of several biological assays to monitor different aspects of the toxic effects, such as viability, genotoxicity, and molecular biomarkers.

Item Type:Article
ID Code:11444
Deposited By:Prof. Alexey Ivanov
Deposited On:05 Jan 2012 09:29
Last Modified:05 Jan 2012 09:42

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