Nano Archive

Novel multi-sided, microelectrode arrays for implantable neural applications

Seymour, John P. and Langhals, Nick B. and Anderson, David J. and Kipke, Daryl R. (2011) Novel multi-sided, microelectrode arrays for implantable neural applications. BIOMEDICAL MICRODEVICES, 13 (3). pp. 441-451. ISSN 1387-2176 (Print) 1572-8781 (Online)

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Official URL: http://www.springerlink.com/content/5rt2vt74l50261...

Abstract

A new parylene-based microfabrication process is presented for neural recording and drug delivery applications. We introduce a large design space for electrode placement and structural flexibility with a six mask process. By using chemical mechanical polishing, electrode sites may be created top-side, back-side, or on the edge of the device having three exposed sides. Added surface area was achieved on the exposed edge through electroplating. Poly(3,4-ethylenedioxythiophene) (PEDOT) modified edge electrodes having an 85-μm2 footprint resulted in an impedance of 200 kΩ at 1 kHz. Edge electrodes were able to successfully record single unit activity in acute animal studies. A finite element model of planar and edge electrodes relative to neuron position reveals that edge electrodes should be beneficial for increasing the volume of tissue being sampled in recording applications.

Item Type:Article
Uncontrolled Keywords:Neural recording – Microelectrode array – Parylene – Neural prostheses – Drug delivery – Chemical mechanical polishing
Subjects:Biomedical Science > Nanobiotechnology
Biomedical Science > Nanomedicine
ID Code:10713
Deposited By:SPI
Deposited On:08 Jun 2011 11:08
Last Modified:08 Jun 2011 11:08

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