Seymour, John P. and Langhals, Nick B. and Anderson, David J. and Kipke, Daryl R. (2011) Novel multi-sided, microelectrode arrays for implantable neural applications. BIOMEDICAL MICRODEVICES, 13 (3). pp. 441-451. ISSN 1387-2176 (Print) 1572-8781 (Online)
Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.
Official URL: http://www.springerlink.com/content/5rt2vt74l50261...
A new parylene-based microfabrication process is presented for neural recording and drug delivery applications. We introduce a large design space for electrode placement and structural flexibility with a six mask process. By using chemical mechanical polishing, electrode sites may be created top-side, back-side, or on the edge of the device having three exposed sides. Added surface area was achieved on the exposed edge through electroplating. Poly(3,4-ethylenedioxythiophene) (PEDOT) modified edge electrodes having an 85-Î¼m2 footprint resulted in an impedance of 200Â kâ¦ at 1Â kHz. Edge electrodes were able to successfully record single unit activity in acute animal studies. A finite element model of planar and edge electrodes relative to neuron position reveals that edge electrodes should be beneficial for increasing the volume of tissue being sampled in recording applications.
|Uncontrolled Keywords:||Neural recording – Microelectrode array – Parylene – Neural prostheses – Drug delivery – Chemical mechanical polishing|
|Subjects:||Biomedical Science > Nanobiotechnology|
Biomedical Science > Nanomedicine
|Deposited On:||08 Jun 2011 11:08|
|Last Modified:||08 Jun 2011 11:08|
Repository Staff Only: item control page