Nano Archive

Lecithin blended polyamide-6 high aspect ratio nanofiber scaffolds via electrospinning for human osteoblast cell culture

Nirmala, R. and Park, Hye-Min and Navamathavan, R. and Kang, Hyung-Sub and El-Newehy, Mohamed H. and Kim, Hak Yong (2011) Lecithin blended polyamide-6 high aspect ratio nanofiber scaffolds via electrospinning for human osteoblast cell culture. Materials Science and Engineering: C, 31 (2). pp. 486-493. ISSN 0928-4931

[img]
Preview
PDF
1506Kb

Official URL: http://www.sciencedirect.com/

Abstract

In this study, we focused on the preparation and characterization of lecithin blended polyamide-6 nanofibers via an electrospinning process for human osteoblastic (HOB) cell culture applications. The morphological, structural characterizations and thermal properties of polyamide-6/lecithin nanofibers were determined by using scanning electron microscopy (SEM), field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, differential scanning calorimetry (DSC) and thermogravimetry (TGA). SEM images revealed that the nanofibers were well-oriented with good incorporation of lecithin. FT-IR results indicated the presence of amino groups of lecithin in the blended nanofibers. TGA analysis revealed that the onset degradation temperature decreased with increasing lecithin content in the blended nanofibers. The morphological features of cells attached on polyamide-6/lecithin nanofibers were confirmed by SEM. The adhesion, viability and proliferation properties of osteoblast cells on the polyamide-6/lecithin blended nanofibers were analyzed by in vitro cell compatibility test. This study demonstrated the non-cytotoxic behavior of electrospun polyamide-6/lecithin nanofibers for the osteoblast cell culture.

Item Type:Article
Subjects:Material Science > Nanofabrication processes and tools
Material Science > Bio materials
Biomedical Science > Nanotechnology for human health
Divisions:Faculty of Engineering, Science and Mathematics > School of Chemistry
ID Code:10585
Deposited By:Associate Prof. Mohamed El-Newehy
Deposited On:01 Feb 2011 19:59
Last Modified:01 May 2011 20:32

Repository Staff Only: item control page