Nano Archive

Preparation of polyamide-6/chitosan composite nanofibers by a single solvent system via electrospinning for biomedical applications

Nirmala, R. and Navamathavan, R. and Kang, Hyung-Sub and El-Newehy, Mohamed H. and Kim, Hak Yong (2011) Preparation of polyamide-6/chitosan composite nanofibers by a single solvent system via electrospinning for biomedical applications. Colloids and Surfaces B: Biointerfaces, 83 (1). pp. 173-178. ISSN 0927-7765

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Abstract

This work was focused on preparation and characterizations of chitosan blended polyamide-6 nanofibers by a new single solvent system via electrospinning process for human osteoblastic (HOB) cell culture applications. The morphological, structural and thermal properties of the polyamide-6/chitosan nanofibers were analyzed by using field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), Fourier transform-infrared (FT-IR) spectroscopy, Raman spectroscopy, differential scanning calorimetry (DSC) and thermogravimetry (TGA). SEM images revealed that the nanofibers were well-oriented and had good incorporation of chitosan. FT-IR results indicated that the amino groups of chitosan existed in the blended nanofibers. TGA analysis revealed that the onset degradation temperature was decreased with increasing chitosan content in the blended nanofibers. The morphological features of the cells attached on nanofibers were confirmed by SEM. The adhesion, viability and proliferation properties of osteoblast cells on the polyamide-6/chitosan blended nanofibers were analyzed by in vitro cell compatibility test.

Item Type:Article
Subjects:Material Science > Nanofabrication processes and tools
Material Science > Bio materials
Biomedical Science > Nanotechnology for human health
Divisions:Faculty of Engineering, Science and Mathematics > School of Chemistry
ID Code:10584
Deposited By:Asst. Prof. Mohamed El-Newehy
Deposited On:01 Feb 2011 19:45
Last Modified:01 May 2011 20:49

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