Nano Archive

Synthesis of water-dispersible photoluminescent silicon nanoparticles and their use in biological fluorescent imaging

Wang, Qi and Ni, Hongjun and Pietzsch, Annette and Hennies, Franz and Bao, Yongping and Chao, Yimin (2011) Synthesis of water-dispersible photoluminescent silicon nanoparticles and their use in biological fluorescent imaging. Journal of Nanoparticle Research, 13 (1). pp. 405-413.

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Official URL: http://www.springerlink.com/content/522473h868nlg7...

Abstract

Water-dispersible silicon nanoparticles (Si-NPs) are desirable for applications in biological techniques. A simplified method to synthesize such particles is reported here. The resulting Si-NPs are water-dispersible and luminescent. Under the excitation of UV light, the Si-NPs emit strong red light with a peak maximum at 606 nm and a quantum yield of 6%. They are highly stable, and remain so over several weeks. Fourier Transform Infrared (FTIR) spectroscopy shows a visible Si–CH2 scissoring vibration mode. Furthermore, the surface chemical bondings were confirmed by X-ray photoelectron spectroscopy (XPS). In the Si2p and C1s core levels, Si–C components are observed. The diameters of the synthesized Si-NPS as measured by atomic force microscope (AFM) are approximately 5 nm. Furthermore, the nanoparticles can be taken up by cultured cells. Fluorescence images of Si-NPs within MCF-7 human breast cancer cells show they are distributed throughout the cell tissue.

Item Type:Article
Subjects:Physical Science > Nanophysics
Physical Science > Nano objects
Material Science > Nanochemistry
Material Science > Nanostructured materials
Divisions:Faculty of Engineering, Science and Mathematics > School of Physics
Faculty of Engineering, Science and Mathematics > School of Chemistry
ID Code:10543
Deposited By:JNCASR
Deposited On:30 Apr 2011 11:46
Last Modified:30 Apr 2011 11:46

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