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Preparation of amino-modified titanate nanotubes and its striking adsorption ability to duplex DNA

Niu, Hongyun and Cai, Yaqi (2011) Preparation of amino-modified titanate nanotubes and its striking adsorption ability to duplex DNA. Journal of Nanoparticle Research, 13 (1). pp. 39-43.

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Official URL: http://www.springerlink.com/content/b38g57124k8612...

Abstract

In this study, amino-modified titanate nanotubes (NH2-TNs) were prepared and used to adsorb duplex DNA. Macroscopic complexes between DNA and NH2-TNs were observed. The uptake of DNA by NH2-TNs was very fast; equilibrium was reached within 10 min at pH 3.6-€“5.0. The equilibrium capacity in the adsorption isotherm of NH2-TNs was 240 mg g-ˆ’1, and further increase of the adsorption capacity was obtained with the addition of Ca2+ in solution. The adsorbed DNA could be released with phosphate buffer saline (PBS) solution without damage of the DNA strands. NH2-TNs could protect DNA from cleavage efficiently in the presence of DNase I.

Item Type:Article
Subjects:Material Science > Functional and hybrid materials
Material Science > Nanochemistry
Divisions:Faculty of Engineering, Science and Mathematics > School of Chemistry
ID Code:10537
Deposited By:JNCASR
Deposited On:30 Apr 2011 12:23
Last Modified:30 Apr 2011 12:23

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