Niu, Hongyun and Cai, Yaqi (2011) Preparation of amino-modified titanate nanotubes and its striking adsorption ability to duplex DNA. Journal of Nanoparticle Research, 13 (1). pp. 39-43.
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Official URL: http://www.springerlink.com/content/b38g57124k8612...
In this study, amino-modified titanate nanotubes (NH2-TNs) were prepared and used to adsorb duplex DNA. Macroscopic complexes between DNA and NH2-TNs were observed. The uptake of DNA by NH2-TNs was very fast; equilibrium was reached within 10 min at pH 3.6-5.0. The equilibrium capacity in the adsorption isotherm of NH2-TNs was 240 mg g-1, and further increase of the adsorption capacity was obtained with the addition of Ca2+ in solution. The adsorbed DNA could be released with phosphate buffer saline (PBS) solution without damage of the DNA strands. NH2-TNs could protect DNA from cleavage efficiently in the presence of DNase I.
|Subjects:||Material Science > Functional and hybrid materials|
Material Science > Nanochemistry
|Divisions:||Faculty of Engineering, Science and Mathematics > School of Chemistry|
|Deposited On:||30 Apr 2011 12:23|
|Last Modified:||30 Apr 2011 12:23|
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